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Protein Coding Gene : Spesp1 sperm equatorial segment protein 1

Primary Identifier  MGI:1913962 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  66712
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Involved in sperm-egg recognition. Acts upstream of or within acrosome reaction and fusion of sperm to egg plasma membrane involved in single fertilization. Located in acrosomal vesicle. Orthologous to human SPESP1 (sperm equatorial segment protein 1).
PHENOTYPE: Heterozygous and homozygous null mutant males show decreased fertilization frequency and delayed fertilization, otherwise homozygous null mice were healthy and showed no overt developmental abnormalities. [provided by MGI curators]
  • synonyms:
  • Spesp1,
  • AI428149,
  • 4921508E09Rik,
  • MGI:2143041,
  • expressed sequence AI428149,
  • sperm equatorial segment protein 1,
  • RIKEN cDNA 4921508E09 gene

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Gene --> Expression annotations

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Disease

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