| First Author | Kong L | Year | 2006 |
| Journal | Biochem Biophys Res Commun | Volume | 339 |
| Issue | 4 | Pages | 1204-7 |
| PubMed ID | 16338220 | Mgi Jnum | J:104204 |
| Mgi Id | MGI:3611512 | Doi | 10.1016/j.bbrc.2005.11.136 |
| Citation | Kong L, et al. (2006) Identification and characterization of mouse PSF1-binding protein, SLD5. Biochem Biophys Res Commun 339(4):1204-7 |
| abstractText | Although most somatic cells cannot proliferate, immature cells proliferate continuously to produce mature cells. Recently, we cloned mouse PSF1 from a hematopoietic stem cell specific cDNA library and reported that PSF1 is indispensable for the proliferation of immature cells. To identify the PSF1-binding protein, we used the yeast two-hybrid system with PSF1 as bait, and identified and cloned SLD5. SLD5 interacted with a central region of PSF1. Tissue distribution of SLD5 was quite similar to that of PSF1. When overexpressed, SLD5 protein was co-localized with PSF1. These data suggest that PSF1 and SLD5 may cooperate in the proliferation of immature cell populations. |
