| Primary Identifier | MGI:3530455 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Lama1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The 7 exons encoding the alphaLm globular (LG) 5 region were removed by fusion of the DraIII and SmaI restriction sites, creating an in-frame deletion. A neo-HSV-tk flanked by loxP sites was inserted downstream of the stop codon and polyA tail. The last 341 residues of the C terminus were deleted and the linker region between alpha1LG3 and alpha1LG4 and a short sequence of the first Beta-strand of the alpha1LG4 domain were left intact. |
