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Protein Coding Gene : Dcdc2a doublecortin domain containing 2a

Primary Identifier  MGI:2652818 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  195208
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable kinesin binding activity. Acts upstream of or within generation of neurons; glutamatergic synaptic transmission; and neuronal action potential. Located in synapse. Is expressed in several structures, including alimentary system; brain; lung; mesonephros; and metanephros. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; dyslexia; nephronophthisis 19; and sclerosing cholangitis. Orthologous to human DCDC2 (doublecortin domain containing 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired short term object recognition, impaired visuo-spatial learning and memory and increased anxiety-related response. [provided by MGI curators]
  • synonyms:
  • MGI:2145433,
  • Dcdc2a,
  • Dcdc2,
  • expressed sequence AW492955,
  • RU2,
  • doublecortin domain containing 2a,
  • AW492955,
  • doublecortin domain containing 2,
  • MGC:54817

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For