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Allele : Phex<tm1.2Mkd> phosphate regulating endopeptidase homolog, X-linked; targeted mutation 1.2, Marc K Drezner

Primary Identifier  MGI:3775079 Allele Type  Targeted
Attribute String  Null/knockout Gene  Phex
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 17 was flanked with a loxP site and a floxed neo cassette via homologous recombination. The neo cassette and exon 17 were subsequently removed via in vivo Cre-mediated recombination. This results in a frameshift, premature termination codon and truncated protein. PCR analysis confirmed the presence of a 0.4 kb truncated transcript in mice carrying this allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele