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Allele : Igf1<tm1.1Dlr> insulin-like growth factor 1; targeted mutation 1.1, Derek LeRoith

Primary Identifier  MGI:2449287 Allele Type  Targeted
Attribute String  Null/knockout Gene  Igf1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  This allele is a derivative of Igf1tm1Dlr in which the loxP flanked sequences were deleted in the germline by crossing mice carrying Igf1tm1Dlr to mice carrying the TgN(EIIa-cre)C5379Lmgd transgene. A truncated, non functional protein is produced.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • KO-HIT,
  • IGF-I -,
  • IGF-I -,
  • KO-HIT
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele