Primary Identifier | MGI:3785556 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Robo4 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2 through 4 were replaced with a human placental alkaline phosphatase gene and a self-excising neo cassette. These exons encode the immunoglobin repeats required for Slit binding. Western blot analysis confirmed the absence of endogenous expression. This is a null and reporter allele. |