| Primary Identifier | MGI:2446285 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 268933 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ubiquitin protein ligase activity. Involved in positive regulation of TORC1 signaling. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR2 complex. Predicted to be active in cytosol and vacuolar membrane. Is expressed in several structures, including adrenal gland; genitourinary system; gut; lung; and spinal cord. Orthologous to human WDR24 (WD repeat domain 24). PHENOTYPE: Homozygosity for a phosphomimetic mutation at Ser155 is early embryonic lethal. Homozygosity for a phosphoblocking mutation at Ser155 affects glucose sensing. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
