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Allele : Pparg<tm1.1Alsb> peroxisome proliferator activated receptor gamma; targeted mutation 1.1, Alexander S Banks

Primary Identifier  MGI:6471170 Allele Type  Targeted
Attribute String  Not Specified Gene  Pparg
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Site-directed mutagenesis was used to alter the codon for serine 273 to alanine (TCA to GCA) (p.S273A). This blocks phosphorylation of that residue in the encoded peptide. A loxP site flanked neomycin resistance gene cassette that was inserted into an intron, was removed through subsequent cre-mediated recombination.
  • mutations:
  • Single point mutation
  • synonyms:
  • PPARgamma<A>,
  • PPARgamma<S273A>,
  • PPARgamma<S273A>,
  • PPARgamma<A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele