Primary Identifier | MGI:6471170 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Pparg |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Site-directed mutagenesis was used to alter the codon for serine 273 to alanine (TCA to GCA) (p.S273A). This blocks phosphorylation of that residue in the encoded peptide. A loxP site flanked neomycin resistance gene cassette that was inserted into an intron, was removed through subsequent cre-mediated recombination. |