| Primary Identifier | MGI:3054941 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Ab1TL)1Gru |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This beta chain transgene expresses a truncated class II A beta molecules that lack the 13 membrane distal residues. Transgene expression was detected on B cells and stimulated macrophages, with the expression on B cells being about a log unit higher than endogenous expression. Immunoprecipitation of B cell lysates confirmed a truncated I-Abeta chain was being expressed. |
