| Primary Identifier | MGI:6367820 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Cct7 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTGCCTGAGAGTTTCCCAAG and TTTGATGTAAAACATGAAAG, which resulted in a 332 bp deletion beginning at Chromosome 6 position 85,461,376 bp and ending after 85,461,707 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000194312 (exon 5) and 279 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 131 and early truncation 31 amino acids later. |
