Primary Identifier | MGI:5308372 | Allele Type | Targeted |
Attribute String | Dominant negative, Humanized sequence, Inserted expressed sequence | Gene | Tnni3 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A C to T transition in codon 21 changed the encoded amino acid from arginine to cysteine. In addition, a floxed neo cassette was inserted in intron 3. Subsequent cre-mediated excision removed the neo selection cassette. |