Primary Identifier | IPR042509 | Type | Family |
Short Name | ZCCHC3 |
description | Zinc finger CCHC domain-containing protein 3 (ZCCHC3) is a zinc-finger protein that acts as a co-sensor of cGAS in innate immune response to cytosolic dsDNA and DNA virus []. It has been shown to bind DNA and RNA in the cytoplasm and acts by promoting recognition of viral nucleic acids by virus sensors, such as DDX58/RIG-I, IFIH1/MDA5 and CGAS [, ]. |