Primary Identifier | MGI:2441849 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 210126 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable metal ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within cell adhesion. Predicted to be located in cytosol. Predicted to be active in focal adhesion and stress fiber. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and musculoskeletal system. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human LPP (LIM domain containing preferred translocation partner in lipoma). PHENOTYPE: Gene disruption results in fertility problems involving females but not males. Migration and survival of MEFs are also abnormal. [provided by MGI curators] |