| Primary Identifier | MGI:7279133 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Atg16l1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Two stop codons in exon 6 were inserted in frame at the end of the sequences encoding the coiled-coil domian (CCD). This mutation allowed translation of glutamate E226 and E230 residues in the CCD required for WIPI2 binding and autophagy, while the linker region and WD (tryptophan-aspartic acid) domain are not expressed. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination in the germline. |
