Primary Identifier | MGI:1935193 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Abca1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 1.9 kb genomic fragment containing exons 19, 20 and part of 21 was deleted and replaced with a neomycin selection cassette. Northern blot and RT-PCR analysis indicated that a truncated transcript is produced from this allele, but any protein produced from this transcript is predicted to be nonfunctional. |