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Publication : A gene-driven approach to the identification of ENU mutants in the mouse.

First Author  Coghill EL Year  2002
Journal  Nat Genet Volume  30
Issue  3 Pages  255-6
PubMed ID  11850622 Mgi Jnum  J:75104
Mgi Id  MGI:2175953 Doi  10.1038/ng847
Citation  Coghill EL, et al. (2002) A gene-driven approach to the identification of ENU mutants in the mouse. Nat Genet 30(3):255-6
abstractText  The construction of parallel archives of DNA and sperm from mice mutagenized with ethylnitrosurea (ENU) represents a potentially powerful and rapid approach for identifying point mutations in any gene in the mouse genome. We provide support for this approach and report the identification of mutations in the gene (Gjb2) encoding connexin 26, using archives established from the UK ENU mutagenesis program.
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