Primary Identifier | MGI:107577 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 226178 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ubiquitin protein ligase binding activity. Acts upstream of or within CXCL12-activated CXCR4 signaling pathway; hemopoiesis; and positive regulation of protein ubiquitination. Predicted to be located in membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system; and integumental system. Orthologous to human WBP1L (WW domain binding protein 1 like). PHENOTYPE: Mice homozygous for a null allele impaired B cell development. [provided by MGI curators] |