Primary Identifier | MGI:2388018 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ambp |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neo-derived cassette replaced exon 7 and the downstream intron via homologous recombination. The neo cassette introduces translation termination codons before serine 7 of the bikunin protein. The alpha 1 microglobulin sequence, which is translated as a fusion protein with bikunin, remains unchanged. |