| First Author | Lichter P | Year | 1992 |
| Journal | Genomics | Volume | 14 |
| Issue | 1 | Pages | 179-80 |
| PubMed ID | 1385299 | Mgi Jnum | J:2541 |
| Mgi Id | MGI:51063 | Doi | 10.1016/s0888-7543(05)80302-7 |
| Citation | Lichter P, et al. (1992) The human APO-1 (APT) antigen maps to 10q23, a region that is syntenic with mouse chromosome 19. Genomics 14(1):179-80 |
| abstractText | The APO-1 (APT) antigen is a cell surface antigen expressed on a variety of normal and malignant cells. Binding of anti-APO-1 antibody to the APO-1 antigen induces programmed cell death (apoptosis). The APO-1 antigen shows homology to the members of the tumor necrosis factor receptor/nerve growth factor receptor superfamily. Using cosmid DNA containing the APO-1 gene as a probe for fluorescence in situ hybridization, we have mapped the gene to a subregion of chromosomal band 10q23. The human APO-1 locus lies within a conserved synteny segment present on mouse chromosome 19 consistent with the previous chromosomal assignment of the corresponding mouse antigen. |
