Primary Identifier | MGI:3623454 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Slc26a6 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to disrupt the locus by replacing parts of exons 2 and 5 and all of exons 3 and 4 with a neomycin resistance cassette. Northern blot of mutant kidney confirmed absence of the major 2.7 kb transcript. Immunoblot confirmed absence of protein in mutants. |