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Protein Coding Gene : Nyap1 neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

Primary Identifier  MGI:2443880 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  243300
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in neuron projection morphogenesis and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Is expressed in central nervous system; neural retina; nucleus pulposus; and spinal ganglion. Orthologous to human NYAP1 (neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1).
PHENOTYPE: Triple KO of Nyap1, Nyap2 and Myo16 results in decreased brain weight and cortex and striatum size and reduced neurite length in cortical neurons. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 6430598A04 gene,
  • 6430598A04Rik,
  • Nyap1,
  • neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

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