|  Help  |  About  |  Contact Us

Protein Domain : Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1

Primary Identifier  IPR026724 Type  Family
Short Name  NYAP1
description  NYAP1 belongs to the neuronal tyrosine-phosphorylated adaptor for the PI 3-kinase (NYAP) family, which consists of NYAP1, NYAP2, NAP3/Myosin16. NYAPs activate PI3K in PI3K pathway, which is a fundamental pathway for various cellular events in neurons. They also interact with components of the WAVE1 complex, which mediates actin cytoskeleton remodeling through Arp2/3 complex. It was suggested that NYAPs connect PI3K activation to WAVE1 signalling in neurons[].

0 Child Features

1 Parent Features

3 Protein Domain Regions