|  Help  |  About  |  Contact Us

Allele : Mapk1<tm3Moga> mitogen-activated protein kinase 1; targeted mutation 3, Masato Ogata

Primary Identifier  MGI:6759774 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence, Reporter Gene  Mapk1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted a floxed IRES-beta-geo fusion cassette, floxed exons 2, a partial cDNA starting from exon 3 to the end of the polyadenylation signal sequence encoding the amino acid substitution of aspartic acid with arginine at position 319 (D319N), and a neomycin resistance cassette. After removing the gene trap cassette by the cre recombinase, the allele expresses a modified protein product with the amino acid substitution.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Mapk1<tm3(D319N)Moga>,
  • ERK2 floxSem,
  • ERK2 floxSem,
  • Mapk1<tm3(D319N)Moga>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele