| Primary Identifier | MGI:1347058 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 26386 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and protein phosphatase binding activity. Predicted to be involved in lens fiber cell differentiation and negative regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nuclear speck. Is expressed in several structures, including brain; lens; respiratory system; submandibular gland; and urinary system. Used to study cataract 5 multiple types. Human ortholog(s) of this gene implicated in cataract and cataract 5 multiple types. Orthologous to human HSF4 (heat shock transcription factor 4). PHENOTYPE: Homozygous null mice display abnormal lens morphology and cataracts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
