Primary Identifier | MGI:6451756 | Allele Type | Targeted |
Attribute String | Inducible, Null/knockout, Recombinase | Gene | Ndrg1 |
Transmission | Germline | Strain of Origin | C57BL/6J |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The targeting vector was designed to insert Cre/ERT2 cassette, polyA tail, and loxP-flanked PGK-Neo cassette in the opposite transcriptional orientation to the first exon of the Ndrg1 gene at the position of the initiation codon. The knock-in allele disrupted the first exon, thereby deleting the expression of Ndrg1. |