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Protein Coding Gene : Bmp6 bone morphogenetic protein 6

Primary Identifier  MGI:88182 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  12161
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable BMP receptor binding activity; protein heterodimerization activity; and receptor ligand activity. Involved in several processes, including multicellular organismal-level iron ion homeostasis; positive regulation of signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including BMP signaling pathway; endochondral ossification; and male genitalia development. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; female reproductive system; skeleton; and visual system. Orthologous to human BMP6 (bone morphogenetic protein 6).
PHENOTYPE: One homozygous null mutant showed delayed ossification in the developing sternum while females of a second null mutant were smaller than normal in size. [provided by MGI curators]
  • synonyms:
  • bone morphogenetic protein 6,
  • Vgr1,
  • DNA segment, Chr 13, Wayne State University 115, expressed,
  • Bmp6,
  • MGI:106333,
  • MGD-MRK-15388,
  • MGD-MRK-15390,
  • MGD-MRK-1604,
  • MGD-MRK-34025,
  • D13Wsu115e,
  • Vg-1 related protein 1

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For