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Protein Domain : Zinc finger CCHC domain-containing protein 3

Primary Identifier  IPR042509 Type  Family
Short Name  ZCCHC3
description  Zinc finger CCHC domain-containing protein 3 (ZCCHC3) is a zinc-finger protein that acts as a co-sensor of cGAS in innate immune response to cytosolic dsDNA and DNA virus []. It has been shown to bind DNA and RNA in the cytoplasm and acts by promoting recognition of viral nucleic acids by virus sensors, such as DDX58/RIG-I, IFIH1/MDA5 and CGAS [, ].

0 Child Features

0 Parent Features

1 Protein Domain Regions