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Publication : Mean corpuscular hemoglobin is not increased in Fmr1 knockout mice.

First Author  Reyniers E Year  1996
Journal  Hum Genet Volume  97
Issue  1 Pages  49-50
PubMed ID  8557260 Mgi Jnum  J:31093
Mgi Id  MGI:78564 Doi  10.1007/BF00218832
Citation  Reyniers E, et al. (1996) Mean corpuscular hemoglobin is not increased in Fmr1 knockout mice. Hum Genet 97(1):49-50
abstractText  A slight increase in mean corpuscular hemoglobin (MCH) has been reported in erythrocytes from human fragile X patients. As it is difficult to perform case-controlled studies in patients with fragile X syndrome, we studied MCH in erythrocytes from transgenic mice with an Fmr1 knockout. None of the knockout mice showed increased MCH levels when compared with normal littermates. We conclude that it is unlikely that the FMR1 gene product has an effect on MCH.
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