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Allele : Ghrl<tm1Suss> ghrelin; targeted mutation 1, Lori Sussel

Primary Identifier  MGI:5485212 Allele Type  Targeted
Attribute String  Null/knockout, RMCE-ready Gene  Ghrl
Transmission  Cell Line Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Positive and negative selection cassettes flanked by modified lox sites were inserted into the Grhl locus by homologous recombination, replacing the region from 2678 bp upstream of exon 1 to 473 bp downstream of exon 5. This creates a locus cassette acceptor (LCA) allele which can be used for recombinase mediated cassette exchange (RMCE) to generate various knock-in alleles.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ghrl-LCA,
  • Ghrl-LCA
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele