Primary Identifier | MGI:2656147 | Allele Type | Targeted |
Attribute String | Hypomorph, Inserted expressed sequence | Gene | Pdgfra |
Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cDNA encoding a mutated receptor consisting of point mutations encoding the tyrosine 572/574 sites was targeted into the Pdgfra locus. Western blot analysis indicated that expression of the targeted Pdgfra locus was disrupted and the mutant receptor was expressed. |