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Publication : The promise of combining inhibition of PI3K and PARP as cancer therapy.

First Author  Rehman FL Year  2012
Journal  Cancer Discov Volume  2
Issue  11 Pages  982-4
PubMed ID  23148373 Mgi Jnum  J:194108
Mgi Id  MGI:5470352 Doi  10.1158/2159-8290.CD-12-0433
Citation  Rehman FL, et al. (2012) The promise of combining inhibition of PI3K and PARP as cancer therapy. Cancer Discov 2(11):982-4
abstractText  Analyses of in vitro and patient-derived in vivo models of breast cancer reveal that a combination of inhibitors of the enzymes PARP and phosphoinositide 3-kinase (PI3K) is a potentially effective treatment regimen for breast cancer tumors with elevated activity of the PI3K pathway.
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