| Primary Identifier | MGI:1344376 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 24099 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable receptor ligand activity. Involved in B cell differentiation and tumor necrosis factor-mediated signaling pathway. Acts upstream of or within several processes, including positive regulation of germinal center formation; positive regulation of lymphocyte activation; and transitional one stage B cell differentiation. Predicted to be located in several cellular components, including focal adhesion; perinuclear region of cytoplasm; and plasma membrane. Predicted to be active in extracellular space. Is expressed in genitourinary system. Orthologous to human TNFSF13B (TNF superfamily member 13b). PHENOTYPE: Homozygous null mice have reduced number of B cells and reduced levels of immunoglobulins. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
