Primary Identifier | MGI:3812191 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(TcraB12,TcrbB12)1Rest |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | RNA was isolated from an I-Ab restricted, Beta-gal specific CD4+ T cell clone. The variable domains for both the Tcra and Tcrb genes were cloned into TCR cassette vectors and co-injected into fertilized embryos. Transgenic mice produce T cells that recognize peptides from the product of the LacZ gene. |