|  Help  |  About  |  Contact Us

Protein Coding Gene : Gpx5 glutathione peroxidase 5

Primary Identifier  MGI:104886 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  14780
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable glutathione peroxidase activity. Acts upstream of or within cellular response to oxidative stress. Located in extracellular space and sperm plasma membrane. Is expressed in several structures, including male reproductive gland or organ and placenta. Orthologous to human GPX5 (glutathione peroxidase 5).
PHENOTYPE: Male mice homozygous for a knock-out allele exhibit age-dependent reduced fertility due to increased sensitivity of sperm DNA to oxidative attack. [provided by MGI curators]
  • synonyms:
  • expressed sequence AV379049,
  • Gpx5,
  • MGI:2145402,
  • androgen regulated epididymal protein,
  • AV379049,
  • MGD-MRK-29039,
  • glutathione peroxidase 5,
  • Arep,
  • MGD-MRK-1389

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For