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Allele : Slpi<tm1Smw> secretory leukocyte peptidase inhibitor; targeted mutation 1, Sharon M Wahl

Primary Identifier  MGI:2386293 Allele Type  Targeted
Attribute String  Null/knockout Gene  Slpi
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence extending from nucleotide -849 through nucleotide 46 was replaced with a neomycin selection cassette. Deletion of this region eliminated regulatory elements, sequence encoding the first 16 amino acids, and introduced a frameshift mutation. Northern blot analysis confirmed the absence of transcript in homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

13 Publication categories

Trail: Allele