| Type | MGI:General | Description | exocytosis in beta cells is impaired; basal exocytosis is reduced by >50% rapidly releasable pool (RRP) of vesicles in beta cells in >50% lower than in wild-type ability of cells to sustain exocitosis in response to repetitive stimulation is reduced compared to wild-type number of exocytotic fusion events is reduced by 50% compared to wild-type cells |