Type | MGI:General | Description | although distribution of extracellular matrix (ECM) molecules such as fibronectin, laminin, and type IV collagen within the palatal shelves is relatively unaffected, tenascin-C is prominently expressed below the presumptive medial epithelial seam (MES) in wild-type fetuses and below the medial epithelial edge (MEE) during cleft palate formation |