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Allele : Rr273<em1Mad> regulatory region 273; endonuclease-mediated mutation 1, Michael A Dyer
Primary Identifier  MGI:7341363 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr273
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  This Vsx2 enhancer was targeted with sgRNAs (GUUAGACCUAGUCAGAACUC and GCAGGCCAUGUGCUCGUCGA) and an ssODN template (TGTAATACCTGTAGTGGCCAGAAGAGGGCATCAGATCCCCAGGAGCTGGAGTACCTACATCTTTGGTTGGTGGTTCAGTCTCTGAGAGCCCCAGGGGCCCAGGTTTGTTGACTCTGTTGG) using CRISPR/Cas9 technology, resulting in a 998 bp deletion (chr12:84578818-84579815 GRCm39).
  • mutations:
  • Intergenic deletion
  • synonyms:
  • R0-37 delta,
  • R0-37 delta
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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