| Primary Identifier | MGI:3865165 | Allele Type | Gene trapped |
| Attribute String | Hypomorph, Modified isoform(s) | Gene | Fstl1 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene trap vector inserted into the second intron of the gene. At 2 months of age, there is an 50% reduction in gene expression in the kidney of the homozygous genetrap mouse compared with wild-type, suggesting that this mutation is a hypomorph. Expression of an alternative transcript of the gene appears to be unaffected by the gene trap insertion, suggesting a mechanism for the hypomorphic mutation. |
