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Protein Coding Gene : Cplx3 complexin 3

Primary Identifier  MGI:2384571 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  235415
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables SNARE binding activity and neurotransmitter transmembrane transporter activity. Involved in insulin secretion; regulation of synaptic vesicle fusion to presynaptic active zone membrane; and synaptic vesicle exocytosis. Acts upstream of or within regulation of neurotransmitter secretion. Located in cytosol; plasma membrane; and synapse. Is active in photoreceptor ribbon synapse; presynaptic active zone membrane; and synaptic vesicle membrane. Is expressed in brain; cerebral cortex; and cortical layer V. Orthologous to human CPLX3 (complexin 3).
PHENOTYPE: Mice homozygous for a null allele are fertile, viable and exhibit normal synaptic transmission. [provided by MGI curators]
  • synonyms:
  • MGC:21420,
  • BC016632,
  • MGC:38804,
  • CpxIII,
  • Cplx3,
  • Lman1l,
  • complexin 3,
  • lectin, mannose-binding, 1 like,
  • cDNA sequence BC016632

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For