| Primary Identifier | MGI:3776761 | Allele Type | Targeted |
| Gene | Slamf1 | Transmission | Germline |
| Strain of Origin | 129 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The loxP flanked neomycin cassette was introduced between exon 1 and 2, then exon 2 encoding the V domain was replaced with the corresponding human sequence. The neo cassette was later excised by cre recombinase expressing transgenic mice. Human SLAM V domain specific MAb confirmed expression of human/mouse chimeric SLAM protein in thymocytes. |
