| Primary Identifier | IPR016367 | Type | Family |
| Short Name | MOM_Lpp |
| description | This entry represents the Major outer membrane lipoprotein (Lpp, also known as murein lipoprotein), which controls the distance between the inner and outer membranes [, ]. This abundant protein contains lipids in its N-terminal which anchor it to the outer membrane. This is the only protein known to bind covalently to the peptidoglycan network (PGN) but it also binds it through non-covalent interactions. About one-third of the Lpp is bound to the cell wall and the rest is free in the periplasm. Lpp have a structural function mediating the interactions between the outer membrane and PGN to assure the correct distance between them and contributes to the structural and functional integrity of the cell membrane []. The role of the periplasm free Lpp remains unknown. |
