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Protein Domain : Metastasis-associated protein MTA2

Primary Identifier  IPR037964 Type  Family
Short Name  MTA2
description  Metastasis-associated protein MTA2 is a component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD) []. It is a member of the MTA family.MTA (metastasis-associated) family members, including MTA1-3, are transcriptional co-repressors that function in histone deacetylation and are involved in the NuRD complex. Nevertheless, MTA1 and MTA2 have been shown to deacetylate non-histone proteins, such as p53. The expression of the MTA family members have been linked to human cancers [].

0 Child Features

1 Parent Features

3 Protein Domain Regions