| Primary Identifier | MGI:98956 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 22416 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables several functions, including identical protein binding activity; signaling receptor binding activity; and transcription coactivator activity. Involved in several processes, including Wnt signaling pathway; negative regulation of cell differentiation; and nervous system development. Acts upstream of or within several processes, including embryonic morphogenesis; nervous system development; and positive regulation of cell population proliferation. Located in cell surface and extracellular space. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; genitourinary system; and sensory organ. Orthologous to human WNT3A (Wnt family member 3A). PHENOTYPE: Homozygous null mutants die at embryonic day 10.5-12.5 with failed development of caudal somites, notochord and structures rostral to hindlimbs. Homozygotes for a hypomorphic allele have vertebral defects and a short tail due to loss of caudal vertebrae. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
