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MP Term : decreased erythrocyte osmotic fragility [MP:0031084] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  decreased propensity of erythrocytes to hemolyze when exposed to increasingly hypotonic saline solutions; seen in chronic liver disease, iron deficiency anemia, thalassemia, hyponatremia, polycythemia vera, and sickle cell anemia after splenectomy
  • synonyms:
  • reduced red blood cell osmotic fragility,
  • increased RBC resistance to osmotic lysis,
  • increased erythrocyte resistance to osmotic lysis,
  • decreased erythrocyte sensitivity to osmotic lysis,
  • reduced erythrocyte osmotic fragility
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

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