Primary Identifier | MGI:3851135 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Kera-PITX2*A)AHjal |
Strain of Origin | (CBA x C57BL/6)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A transgenic construct containing cDNA for the human paired-like homeodomain 2, human, PITX2, A isoform, under the control of the mouse keratocan (Kera) promoter, and rabbit beta-globin polyA signal sequences was injected into fertilized CBAB6F2 mouse eggs. Numerous founders were obtained. In line A, multiple copies were found to be integrated into chromosome 10B1. Lines A and B display identical phenotypes. |