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Allele : Del(7Ipw-Snord116)1Jbro deletion, chr 7, Jurgen Brosius 1
Primary Identifier  MGI:4356431 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(7Ipw-Snord116)1Jbro
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing the 5' half of the HPRT mini-gene, a loxP site and a neomycin resistance gene was inserted 5' of Snord116 (Snord116tm1Jbro) and a cassette containing a puromycin resistance gene gene, a loxP site, and the 3' half of the HPRT mini-gene was inserted 3' of Ipw (Ipwtm1Jbro). Transient cre expression in ES cells deleted both genes/gene clusters. This region is termed the Prader-Willi Syndrome critical region (PWScr).
  • mutations:
  • Insertion,
  • Intragenic deletion,
  • Intergenic deletion
  • synonyms:
  • Del1Jbro,
  • PWScr<->,
  • Del1Jbro,
  • PWScr<->
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1 Feature

Genome

0 Expresses

68 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories





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