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Allele : Adamts17<tm1.2Taks> ADAM metallopeptidase with thrombospondin type 1 motif 17; targeted mutation 1.2, Taku Saito
Primary Identifier  MGI:6466717 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adamts17
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 4, and an FRT-flanked neomycin selection cassette and a second loxP site were inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and cre-mediated recombination in the germline deleted exon 4. Deletion of exon 4 generates a frame-shift leading to disruption of the zinc-dependent metalloprotease domain and its downstream sequences.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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4 Publication categories

Trail: Allele




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