Primary Identifier | MGI:5004939 | Allele Type | Chemically induced (ENU) |
Gene | Aldh1a2 | Strain of Origin | 129S1/Sv or C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A T-to-C base pair change in intron 4 of the gene disrupts splicing and leads to premature termination of translation of the encoded protein. Quantitative RT-PCR indicates expression in homozygotes is less than 1% that in wild-type embryos. |